# Doc conversation help? New here

**URL:** <https://forum.livingwitherythromelalgia.org/t/doc-conversation-help-new-here/4765>\
**Category:** New Member Introductions\
**Created:** [March 30, 2020, 9:35pm UTC](https://forum.livingwitherythromelalgia.org/t/doc-conversation-help-new-here/4765 "2020-03-30T21:35:03Z")\
**Posts on this page:** 1\
**Showing post:** 8

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**Author:** ![CarterDK](https://avatars.discourse-cdn.com/v4/letter/c/0ea827/32.png) [@CarterDK](https://forum.livingwitherythromelalgia.org/u/CarterDK)\
**Post date:** [April 1, 2020, 7:28pm UTC](https://forum.livingwitherythromelalgia.org/t/doc-conversation-help-new-here/4765/8 "2020-04-01T19:28:59Z")

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I wrote a new post yesterday about my mexiletine dosing and it answers a lot of your questions. That post can be found here: [MEXILETINE reduction](https://forum.livingwitherythromelalgia.org/t/mexiletine-reduction/4768).

I titrated up my initial mexiletine dosing by taking a single 150 mg pill daily the first week, then two 150mg pills daily the next week, followed by three 150mg pills daily thereafter. However, I found most benefit came from the single daily 150 mg dose. Improvement was immediate and dramatic from the single daily dose. Prior to mexiletine therapy I was flaring multiple times a day, every day. I experienced symptoms every 2-4 hours. That flaring cycle stopped 36 hours after the initial dose. I have experienced only a handful of minor flares per year since and those that do occur are both less painful and more easily mitigated. I do still have occasional paresthesia at night (pins and needles feeling) if I get too hot while sleeping under bedding. That can be eliminated simply by removing the covering.

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