# Mexiletine not good yet

**URL:** <https://forum.livingwitherythromelalgia.org/t/mexiletine-not-good-yet/6046>\
**Category:** Symptoms and Treatments\
**Created:** [November 9, 2022, 11:03pm UTC](https://forum.livingwitherythromelalgia.org/t/mexiletine-not-good-yet/6046 "2022-11-09T23:03:59Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![emhelp](https://avatars.discourse-cdn.com/v4/letter/e/e5b9ba/32.png) [@emhelp](https://forum.livingwitherythromelalgia.org/u/emhelp)\
**Post date:** [November 9, 2022, 11:03pm UTC](https://forum.livingwitherythromelalgia.org/t/mexiletine-not-good-yet/6046/1 "2022-11-09T23:03:59Z")

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I was on Venlafaxine for almost a year. It helped the physical symptoms but made me a little goofy. So I started Mexiletine oral 150 mg twice a day. I have been on this for maybe 6 weeks. I have noticed limited improvement during the day but big time flares start about 1/2 hour after going to bed. I see the doctor next week. He mentioned increased dosage and/or infusion. We’ll see.