Exercise Intolerance & Dysautonomia are daily battles for me. I’m only 50 yrs old and have just undergone a CPET test (the attached article describes this). I tested out as normal with the QSART Tilt Table testing, but my neurologist believed that there was more going on and didn’t take the “normal” results as what was really going on. I went to Brigham and Women’s Hospital in Boston and saw Dr. Systrom. He said that my testing shows that I have Dysautonomia and that there is a potential medication that could make all the difference…Mestinon. Unfortunately I am having difficulty tolerating the side effects of merely 90 mg daily. Nausea, overheating, diarrhea and headaches…I have the genetic variant form of small fiber neuropathy that is coupled with Erythromelalgia - I have tried sodium channel blockers, all failing due to bad side effects… now I am waiting for a call from Mass General Hospital to have me come in for a series of Lidocaine infusions. This is important information and testing for anyone with POTS or anyone who suspects that they have dysautonomia that may not be apparent right away with basic Tilt Table testing…
Interesting article. My aunt has suffered from exercise intolerance for years. Despite seeing over a dozen doctors, she has not found relief. She was recently diagnosed with POTS and given IV saline to expand blood volume, but has not found it effective.