I'm very sorry to hear you're having such trouble with your EM as well as your injury. I wanted to reply because my EM history is similar to Alina's. I'd also like to highlight the importance of early diagnosis of EM (which did not happen with me) as well as the role of slow titration of medication in helping EM sufferers deal with pain while decreasing the number and severity of unwanted side effects.
When I was in my 30s I had mild Renauds in hands and feet, but after menopause I developed hot feet and hands. I had very mild EM for many years without knowing what it was. It came on if I did a lot of exercise and became very warm, but it resolved on its own fairly quickly.
Then I developed a small tumor under my right foot--a genetic defect that caused blood vessels and nerves to intermingle resulting in some serious pain. It also caused blood to back up when the area was inflamed. One of these episodes occurred when I was returning home to Canada from Europe. The air travel triggered blood clots and I developed a nasty phlebitis which took several months to settle down. After that my right foot would sometimes flare if I stood too long. Of course ice and elevation were prescribed to reduce the swelling since heat made the phlebitis much worse. The tumor grew and became inflamed at times which provoked more blood clots. It was deemed inoperable and specialists told me the only option that might work was sclerotherapy (IV injection of acid or caustic substances into veins to kill blood vessels and tumors).
Because no one knew what the implications of that procedure would be on EM, I believe it was the major trigger for a new "level" of EM. While it helped reduce the size of the tumor, it triggered massive phlebitis and EM in my right foot and leg. Again the only relief came from ice packs several times per day. Eventually things settled down but I noticed that both feet were now flaring (feeling hot and full, but not painful) after too much walking or heat. However, cool water baths resolved the problem very quickly.
Eventually, it settled down to a few flares each day when I was too warm or in the night. But then I got a nasty eye infection and a low grade fever for 2-3 days. The fever caused massive flares and extreme burning pain in both feet for the first time! It was downhill after that. Within a couple of weeks I had constant flares and excruciating pain at night and severe pain the rest of the time. That went on for 3-4 months and I finally decided I would be willing to take medication.
Dr. Jay Cohen in California helped me and my wonderful new family doctor test various supplements and medications starting with the least intrusive and then finally moving into heavier artillery. Eventually, he recommended Lyrica. I started on only 6.25 mg/day of Lyrica and titrated it slowly. At only 18.75 mg/day, I was able to sleep for 2-3 hours at a time. By the time I got to 60mg I could sleep the night. (This shows how important gradual titration can be to finding the right dose. Doctors in North America tend to start at the recommended dose which can be way too high for many people and cause unnecessary side effects).
I am currently on just over 100mg of Lyrica/day spread over 5 doses. I find that taking Lyrica every 3+ hours handles the pain much better than larger doses every 4-6 hours. We are now very gradually adding Cymbalta to the mix because I was unable to tolerate any higher dose of Lyrica. I am still only at 15mg of Cymbalta which is only half the lowest dose available in Canada. It really helps with daytime pain and seems to work in synergy with Lyrica in reducing the number and duration of flares I have per day.
Although I am far from being flare and pain free, I am much better than I was a year ago. The exciting thing is that Cymbalta seems to improve circulation so that my feet are much less swollen (Lyrica tends to make feet swell!) and my skin is beginning to heal and toenails are starting to grow back. However, I believe that I may be near the the maximum toleration level of Cymbalta as I am experiencing some cardiac symptoms that do not seem to be settling down. So, we are looking at adding an antihistamine to the mix to see if blocking histamine may help. Combination pharmacy seems to help many of us deal with the various problems we encounter with EM.
Finding the right medication is usually a matter of trial and error and lots of patience. And finding ways to manage stress and fear of pain and EM are also very important. We've got to keep our amygdalas calm so they don't activate the stress response every time we are experiencing pain. MIndfulness meditation, EFT (Tapping) and self-hypnosis have helped me tremendously. I practice them several times every day and find that my attitude toward pain and disability is much better and my mood has improved.
I wish you all the best in your search for effective pain relief.